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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNJ13
All Species:
17.88
Human Site:
S221
Identified Species:
39.33
UniProt:
O60928
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60928
NP_002233.2
360
40530
S221
N
G
K
L
Y
Q
T
S
V
D
F
H
L
D
G
Chimpanzee
Pan troglodytes
XP_513920
628
69490
Q482
G
E
N
I
R
L
N
Q
V
N
V
T
F
Q
V
Rhesus Macaque
Macaca mulatta
XP_001114522
360
40512
S221
N
G
K
L
Y
Q
T
S
V
D
F
H
L
D
G
Dog
Lupus familis
XP_534607
360
40479
S221
N
G
E
L
N
Q
T
S
V
D
F
H
L
D
G
Cat
Felis silvestris
Mouse
Mus musculus
P86046
360
40546
S221
N
G
E
L
Y
Q
T
S
V
D
F
H
L
D
G
Rat
Rattus norvegicus
O70617
360
40618
S221
N
G
E
L
Y
Q
T
S
V
D
F
H
L
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509904
569
64097
A427
E
R
I
L
L
N
Q
A
S
V
K
F
H
V
D
Chicken
Gallus gallus
P52186
427
48500
E247
G
E
Y
I
P
L
D
E
I
D
I
N
V
G
F
Frog
Xenopus laevis
NP_001088081
378
42640
Q233
G
E
N
V
H
L
N
Q
I
N
V
D
F
Q
V
Zebra Danio
Brachydanio rerio
NP_001039014
362
40552
R224
S
A
V
L
Y
E
E
R
D
D
H
E
L
H
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52192
505
57401
E280
I
E
P
L
H
Q
F
E
M
K
V
G
P
S
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.3
98.6
96.6
N.A.
93
93.8
N.A.
24.7
30.9
37.8
48.9
N.A.
N.A.
N.A.
27.3
N.A.
Protein Similarity:
100
34.8
99.7
98.3
N.A.
97.2
97.2
N.A.
36.2
49.4
55.5
66
N.A.
N.A.
N.A.
43.9
N.A.
P-Site Identity:
100
6.6
100
86.6
N.A.
93.3
93.3
N.A.
6.6
6.6
0
26.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
20
100
93.3
N.A.
100
100
N.A.
13.3
33.3
26.6
40
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
10
64
0
10
0
46
10
% D
% Glu:
10
37
28
0
0
10
10
19
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
46
10
19
0
10
% F
% Gly:
28
46
0
0
0
0
0
0
0
0
0
10
0
10
46
% G
% His:
0
0
0
0
19
0
0
0
0
0
10
46
10
10
0
% H
% Ile:
10
0
10
19
0
0
0
0
19
0
10
0
0
0
10
% I
% Lys:
0
0
19
0
0
0
0
0
0
10
10
0
0
0
0
% K
% Leu:
0
0
0
73
10
28
0
0
0
0
0
0
55
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
46
0
19
0
10
10
19
0
0
19
0
10
0
0
0
% N
% Pro:
0
0
10
0
10
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
55
10
19
0
0
0
0
0
19
10
% Q
% Arg:
0
10
0
0
10
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
46
10
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
46
0
0
0
0
10
0
0
0
% T
% Val:
0
0
10
10
0
0
0
0
55
10
28
0
10
10
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
46
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _